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KMID : 0853020140170010025
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Journal of Korean Burn Society
2014 Volume.17 No. 1 p.25 ~ p.29
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Effect of Plant Extracts Contained Dressing Material Which Is Rich in Procyanidins for Treatment of Deep Second Degree Burn
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Lee Young-Joo
Yoon Jae-Chul
Yang Hyeong-Tae
Cho Yong-Suk
Kim Do-Hern
Kim Jong-Hyun
Hur Jun
Chun Wook
Yim Hae-Jun
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Abstract
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Purpose:This study was planned to evaluate the effect of plant extracts contained dressing material which is rich in procyanidins for treatment of deep second degree burn.
Methods: This study conducted from September 1, 2013 to February 28, 2014. Patients with the deep dermal burn wound which is larger than 200 cm2 were enrolled in this study. The test material was applied total 3 times every 2 days when the wounds were relatively clean, with thin eschar and scab removed and the dermal layer exposed. The test and control sites were treated with hydro-foam equally. The effectiveness was evaluated by comparing the re-epitheliali-zation rates between the test and control sites. Two burn sur-geons blindly evaluated for re-epithelialization. Evaluation of adverse reaction was also performed during study period.
Results: Total of 40 patients were enrolled. Mean total body surface area burned% was 12.3±5.5% and the test material was first applied at mean post burn day # 7.2±2.0.The re-epi-thelialization period was 9.0±1.7 days in the test site and 11.1±2.0 days in the control site. In the test site, re-epitheliali-zation was 2.1±1.0 days faster than in the control site (P＜ 0.0001). There was no significant adverse reaction during study period.
Conclusion: The plant extracts contained dressing material which is rich in procyanidins accelerates wound healing time and shows the safety.
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KEYWORD
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Deep second degree burn, Procyanidin
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